A-RING addresses the overall need to pool efforts in tackling major challenges with joint Research and Innovation (R&I) approach steering EU Open Innovation path. It fosters alignment between different R&I policy initiatives and institutional frameworks to effectively address societal challenges, increases the uptake of strengths and assets, and gathers expectations from Business Sector and innovation potential from Academia, granting citizens’ needs linked to responsible R&I (RRI). A-RING aims to increase the level of application of multilevel and transnational governance in the Alpine Space with the right policy mix achieved in coherence with the Public Authorities’ vision, their synergic and/or complementary approach on S3 strategies and improved environment for the collaboration including Academia and Business Sector.